canada drugs

Welcome to CanDrug
Discount Canadian Pharmacy

Drug Search
Alphabetical List



Chemical Name : Entacapone

Comtan Information : Parkinson's medication Comtan (Entacapone) is used to help in the treatment of Parkinson's disease (PD). Comtan (Entacapone) is a member of a class of medications called catechol O-methyltransferase inhibitors. More simply, these medications are called COMT inhibitors. When taken properly, Comtan (Entacapone) works to make the benefits of Sinemet (carbidopa/levodopa) therapy last longer. Adding Comtan (Entacapone) could help Sinemet (carbidopa/levodopa) work better than levodopa/carbidopa alone and can mean a greater improvement in the control of PD symptoms.

Comtan Side Effects : Most commonly reported Comtan side effects were unwanted or uncontrolled movements, nausea, urine discoloration, diarrhea, and abdominal pain. In response to some of these Comtan side effects, your doctor may advise you to reduce your dosage of levodopa. If you take nonselective MOA inhibitors (eg, phenelzine, tranylcypromine) you should not take COMTAN otherwise they may result in Comtan side effects. COMTAN should not be taken with selegiline at doses higher than 10mg/day otherwise they may result in Comtan side effects. If you taking any drugs that are broken down by COMT, (eg, isoproterenol, epinephrine) your doctor will want to use COMATN with caution. Some of the more serious Comtan side effects that have been reported with COMTAN include low blood pressure, diarrhea, hallucinations, and unwanted or uncontrollable movements. If you have any Comtan side effects like liver problems your doctor will want to use COMTAN with caution, as your condition can affect the way your body breaks down COMTAN.

The COMT enzyme is a substance in the body that breaks down levodopa before it can get to the brain. By blocking the COMT enzyme, COMTAN helps more levodopa become available to the brain. When levodopa reaches the brain, it is converted into dopamine (DOPE-a-meen). Dopamine is the chemical that helps the brain control activities, such as walking, talking, and moving. People who have Parkinson's disease (PD) don't produce enough dopamine. In addition, the cells in the brain that make dopamine aren't working properly. That's why you are taking carbidopa/levodopa medicine. Once levodopa reaches the brain, it is converted into dopamine. Supplementing dopamine in the brain by taking levodopa can help control PD symptoms-enabling people to pursue daily tasks, such as dressing, walking, and handling utensils.

The generic alternative is not manufatured by the company that makes the brand product.

The content on this page has been supplied to by an independent third party contracted to provide information for our website. CanDrug relies on these third parties to create and maintain this information and cannot guarantee the medical efficacy, accuracy or reliability of the information that has been provided to us. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a health professional. Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We affiliate with other dispensaries that ship product to our customers from the following jurisdictions: Canada, Singapore, New Zealand, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.

Back to Main Drug Information Page

In addition to having your prescriptions dispensed from our affiliated Canadian dispensing pharmacy, your medications are also dispensed from international pharmacies and fulfillment centers that are approved by the regulatory bodies in their respective countries. works with fulfillment centers in a variety of countries including but not limited to Canada, New Zealand, Australia, Turkey, Mauritius, India, and the United Kingdom. All prices are in US dollars.