Zonisamide is an anticonvulsant used to control certain type of seizures.
Do not take zonisamide without first talking to your doctor. If you have ever had an allergic reaction to a sulfa drug such as sulfamethoxazole (Gantanol, others); sulfisoxazole (Gantrisin, others); or sulfamethoxazole-trimethoprim (Bactrim, Bactrim DS, Septra, Septra DS, Cotrim, others) - you may also have an allergic reaction to zonisamide.
Other, less serious side effects may be more likely to occur. Continue to take zonisamide and talk to your doctor if you experience:
dizziness;
mild drowsiness;
loss of appetite;
headache;
nausea;
agitation or irritability.
If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
a rash;
increasing frequency or worsening of seizures;
fever, sore throat, sores in your mouth, or bruising easily (may be signs of a blood problem);
sudden back pain, stomach or abdominal pain, pain when urinating, bloody or dark urine (may be signs of a kidney stone);
decreased sweating or a rise in body temperature (especially in those under 17 years old);
depression;
severe drowsiness, difficulty concentrating, or coordination problems;
unusual thoughts; or
speech or language problems including difficulty finding words.